Oh, it's Astro's dog house. Okay.
What's wrong with this picture? So very much. The antenna on the roof, perhaps. The perspective that makes Elroy look as large as his parents. George's apparent displeasure with Astro, as if this is his fault. The cloud of dust left by Elroy. The design of the dog house that would make it nearly impossible for Astro to get comfortable without falling down the tube, let alone get up the tube in the first place.
Yes, that's about it. Can't think of anything else peculiar about the illustration. No sir. Not at all.