Apolinario Mabini, “The Sublime Paralytic.” Really: he lost the use of his lower limbs in his thirties, but it didn’t affect his brain. He was the Philippine’s first prime minister, and wrote the first constitution. More here.

Frankly, he looks like one of those bloodless guys who turns up in every revolution and drafts the plans to put half the political class in camps and the other half in the ground, but that's just my first take.